About Liposome Calculator
Liposome Calculator is a tool for preparation and parameterization of lipid and other surfactant suspensions (liposomes, multilamellar vesicles, etc.). It is particularly useful for model membrane, drug delivery and...
Liposome Calculator is a tool for preparation and parameterization of lipid and other surfactant suspensions (liposomes, multilamellar vesicles, etc.).
It is particularly useful for model membrane, drug delivery and molecular interaction research.
For details please refer to www.volard.wordpress.com
The application follows the common liposome preparation procedure, as depicted in www.volard.wordpress.com:
(1) Stock solutions of lipids (or any other compound) are mixed in an appropriate molar ratios.
(2) Obtained mixture is purged with nitrogen and organic solvent is finally evacuated under vacuum.
(3) Obtained lipid mixture is hydrated and extruded or sonicated, according to the needs.
Application helps to fully parameterize the complex lipid mixture system, providing user with complete information regarding preparation procedure.
Concentrations (molarity and mg/ml), components moles, final solution volume etc. are calculated based upon initial data provided, such as: initial concentrations of the stock solutions, initial volumes and desired molar ratios.
Application includes customizable database for storing molecular weights of the frequently used compounds. Upon typing of solute names into component cells the software will suggest to autocomplete with stored information from the database.
Liposome Formulation can be stored and restored.
Application is fully interactive: all system parameters are updated immediately after any input from user (if it is sufficient!). For example: final molar concentration and molar ratios of the components can be adjusted at any time if molar concentrations of starting solutions and final suspension volume are provided.
Upon any of the aforementioned changes, the application will calculate the volumes of the initial solutions to fit the desired parameters.
Infinite number of components can be added by touching “(+) ” menu button and deleted by touching the “(-)” button.
If molecular weights (Mw, units "g/mole") of solutes are provided as well, then concentrations in the units of grams of solute per litre of solution ("g/l" equivalent to "mg/ml") can be calculated.
Previous Versions
Here you can find the changelog of Liposome Calculator since it was posted on our website on 2016-10-29 17:27:38.
The latest version is 6.3 and it was updated on 2024-04-22 10:03:36. See below the changes in each version.
Liposome Calculator version 6.3
Updated At: 2023-04-03
Liposome Calculator version 5.0
Updated At: 2016-10-17
Changes: Unlimited number of components is available. Additional components are added by touching “(+) Solution (of)” field and deleted by touching the final “Moles (-)” field.,Complex formulations can now be stored and restored.,The application is now capable to characterize single vesicle parameters, like entrapped volume, surface area and number of molecules in the liposome.
Disclaimer
Official Google Play Link
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